Article
ICP0, a regulator of herpes simplex virus during lytic and latent infection
24 Jul 2000
Abstract excerpt
Cold sores produced by HSV-1 infection are an annoying but trivial recurrent problem for most of us, but the virus can also cause more serious disease. Episodes of active HSV-1 infection, in response to stress or sunlight, are possible because the virus establishes a latent infection in neurones which can not be eliminated. Since vigorous transcription from the whole viral genome during lytic infection contrasts...
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