Article
C3 as substrate for adhesion of Streptococcus pneumoniae.
The Journal of infectious diseases - 1 Aug 2000
Smith B L, Hostetter M K
Abstract excerpt
The ability of choline-binding protein A (CbpA) of Streptococcus pneumoniae to bind the third component of complement (C3) suggests possible interactions with opsonic C3 in the bloodstream or with C3 secreted by epithelial cells. The latter possibility was investigated by measuring C3 in supernatants of resting and cytokine-activated monolayers of type II pulmonary epithelial cells (A549 cells). Expression of C3...
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