Article
Aplastic anemia is associated with HLA-DRB1*1501 in northern Han Chinese.
International journal of hematology - 1 Jun 2000
Shao W, Tian D, Liu C, Sun X, Zhang X
Abstract excerpt
It has been reported that aplastic anemia (AA) is more common in HLA-DR2-positive individuals than in the general population. We investigated the frequency of some HLA loci of 102 Northern Han Chinese patients with AA and 105 healthy control subjects. Polymerase chain reaction and sequence specific oligonucleotide probe hybridization were used to determine HLA-DR- and HLA-DR2-related DRB1 alleles. The frequency...
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