Article
[Correlation of HLA-alleles with aplastic anemia].
Zhongguo shi yan xue ye xue za zhi - 1 Dec 2007
Liang Xiao-Lan, Qiu Lu-Gui, Sun Le-Jing, Yu Li-Jia, Han Jun-Ling, Li Qian
Abstract excerpt
To investigate the correlation between the HLA genes and pathogenesis of aplastic anemia (AA), polymerase chain reaction with specific sequence primers (PCR-SSP) method was used to HLA typing in 82 patients with AA and 400 normal healthy individuals as control. The results showed that A*2301 (1.84%), B*5501 (4.36%) and DRB1*0901 (23.48%) gene frequency in AA patients were significantly higher than those in...
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