Article
Mouse fzd4 maps within a region of chromosome 7 important for thymus and cardiac development.
Genesis (New York, N.Y. : 2000) - 1 Jun 2000
DeRossi C, Laiosa M D, Silverstone A E, Holdener B C
Abstract excerpt
The cardiac neural crest (CNC) plays a central role in development of the thymus gland and cardiovascular system. Through morphological and histological characterization of embryos homozygous for the Del(7)Tyr(c-112K) and Del(7)Tyr(c-3H) albino deletions, we identified abnormalities that are consistent with aberrant development of tissues requiring CNC contributions. The defects include incompletely penetrant...
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