Article
Polymorphisms in the vitamin D receptor gene and bone mass, bone turnover and osteoporotic fractures.
European journal of clinical investigation - 1 Jul 2000
Langdahl B L, Gravholt C H, Brixen K, Eriksen E F
Abstract excerpt
BACKGROUND: Vitamin D is essential for normal bone metabolism. Polymorphisms in exon 2, intron 8 and exon 9 of the vitamin D receptor (VDR) gene have previously been found to be associated with bone mass and bone turnover. MATERIALS AND METHODS: We examined the effect of these polymorphisms, separately and in combination, on bone mineral density (BMD), bone turnover, and the prevalence of osteoporotic fractures...
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