Article
Genetic Determinants of Vitamin D-Related Disorders; Focus on Vitamin D Receptor.
Current drug metabolism - 1 Jan 2018
Abouzid Mohamed, Karazniewicz-Lada Marta, Glowka Franciszek
Abstract excerpt
BACKGROUND: The endocrine system of vitamin D is involved in an extensive variety of biological processes such as bone metabolism, regulation of cell proliferation and differentiation and modulation of the immune response. The active form of vitamin D, 25-hydroxyvitamin D, binds to vitamin D receptor (VDR) controlling the synthesis of many different proteins. Although numerous studies reported polymorphism in the...
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