Article
Molecular identification of a taste receptor gene for trehalose in Drosophila.
Science (New York, N.Y.) - 7 Jul 2000
Ishimoto H, Matsumoto A, Tanimura T
Abstract excerpt
The molecular nature of sweet taste receptors has not been fully explored. Employing a differential screening strategy, we identified a taste receptor gene, Tre1, that controls the taste sensitivity to trehalose in Drosophila melanogaster. The Tre1 gene encodes a novel protein with similarity to G protein-coupled seven-transmembrane receptors. Disruption of the Tre1 gene lowered the taste sensitivity to...
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