Article
Mutants in phospholipid signaling attenuate the behavioral response of adult Drosophila to trehalose.
Chemical senses - 1 Oct 2010
Kain Pinky, Badsha Farhath, Hussain Syed Mubarak, Nair Amit, Hasan Gaiti, Rodrigues Veronica
Abstract excerpt
In Drosophila melanogaster, gustatory receptor genes (Grs) encode putative G-protein-coupled receptors (GPCRs) that are expressed in gustatory receptor neurons (GRNs). One of the Gr genes, Gr5a, encodes a receptor for trehalose that is expressed in a subset of GRNs. Although a role for the G protein, Gsα, has been shown in Gr5a-expressing taste neurons, there is the residual responses to trehalose in Gsα mutants...
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