Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetically perpetuated human neural stem cells engraft and differentiate into the adult mammalian brain.

Molecular and cellular neurosciences - 1 Jul 2000

Rubio F J, Bueno C, Villa A, Navarro B, Martínez-Serrano A

Abstract excerpt

Human neural stem cells (HNSCs) may serve as a cellular vehicle for molecular therapies as well as for cell replacement in the human CNS. The survival, integration, and differentiation of HNSC.100, a multipotent cell line of HNSCs (A. Villa et al. (2000), Exp. Neurol. 161, 67-84), conditionally perpetuated by genetic and epigenetic means, was investigated after transplantation to the striatum and substantia nigra...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoradiography
Share to Corpus Striatum
Share to Graft Survival

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intermediate Filament Proteins

Share to Nestin

Share to Stem Cell Transplantation

Share to Substantia Nigra

Share to Transplantation, Heterologous

Source

Identifiers

PMID: 10882478
DOI: 10.1006/mcne.2000.0854

Genes

GFAP
MAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetically perpetuated human neural stem cells engraft and differentiate into the adult mammalian brain.PMID 10882478Read ↗

Epigenetic conversion of human adult bone mesodermal stromal cells into neuroectodermal cell types for replacement therapy of neurodegenerative disordersSemantic proximity Read ↗

Establishment and properties of a growth factor-dependent, perpetual neural stem cell line from the human CNS.Semantic proximity Read ↗

Efficient generation of neural stem cell-like cells from adult human bone marrow stromal cellsSemantic proximity Read ↗

Neural Stem Cells: From Neurobiology to Clinical ApplicationsSemantic proximity Read ↗

Pluripotent stem cells engrafted into the normal or lesioned adult rat spinal cord are restricted to a glial lineage.Semantic proximity Read ↗

Migration patterns and phenotypic differentiation of long-term expanded human neural progenitor cells after transplantation into the adult rat brain.Semantic proximity Read ↗

Survival, integration, and differentiation of neural stem cell lines after transplantation to the adult rat striatum.Semantic proximity Read ↗

In vivo Ontogeny of human forebrain neural progenitor cell grafts in adult rats: an immunohistological studySemantic proximity Read ↗

Adherent Neural Stem (NS) Cells from Fetal and Adult ForebrainSemantic proximity Read ↗

Generation of human cortical neurons from a new immortal fetal neural stem cell line.Semantic proximity Read ↗

The adult substantia nigra contains progenitor cells with neurogenic potential.Semantic proximity Read ↗

Dopaminergic neurons from midbrain-specified human embryonic stem cell-derived neural stem cells engrafted in a monkey model of Parkinson's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.