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Article

Parkin and relatives: the RBR family of ubiquitin ligases

19 May 2004

Abstract excerpt

Mutations in the parkin gene cause autosomal-recessive juvenile parkinsonism. Parkin encodes a ubiquitin-protein ligase characterized by having the RBR domain, composed of two RING fingers plus an IBR/DRIL domain. The RBR family is defined as the group of genes whose products contain an RBR domain. RBR family members exist in all eukaryotic species for which significant sequence data is available, including...

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PMID: 15152079
DOI: 10.1152/physiolgenomics.00226.2003

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Parkin and relatives: the RBR family of ubiquitin ligasesPMID 15152079Read ↗

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