Article
Autonomously replicating macronuclear DNA pieces are the physical basis of genetic coassortment groups in Tetrahymena thermophila.
Genetics - 1 Jul 2000
Wong L, Klionsky L, Wickert S, Merriam V, Orias E, Hamilton E P
Abstract excerpt
The macronucleus of the ciliate Tetrahymena thermophila contains a fragmented somatic genome consisting of several hundred identifiable chromosome pieces. These pieces are generated by site-specific fragmentation of the germline chromosomes and most of them are represented at an average of 45 copies per macronucleus. In the course of successive divisions of an initially heterozygous macronucleus, the random...
Topics
- Alleles
- Animals
- Cell Nucleus
- DNA Replication
- DNA, Protozoan
- Inbreeding
- Phenotype
- Polymorphism, Genetic
- Random Amplified Polymorphic DNA Technique
- Tetrahymena thermophila