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Article

The Saccharomyces cerevisiae RDN1 locus is sequestered from interchromosomal meiotic ectopic recombination in a SIR2-dependent manner.

Genetics - 1 Jul 2000

Davis E S, Shafer B K, Strathern J N

Abstract excerpt

Meiotic ectopic recombination occurs at similar frequencies among many sites in the yeast genome, suggesting that all loci are similarly accessible to homology searching. In contrast, we found that his3 sequences integrated in the RDN1 (rDNA) locus were unusually poor participants in meiotic recombination with his3 sequences at other sites. We show that the low rate of meiotic ectopic recombination resulted from...

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Identifiers

PMID: 10880466
DOI: 10.1093/genetics/155.3.1019
PMCID: PMC1461158

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