Article
Characterization of loose and tight dimer forms of avian leukosis virus RNA.
Journal of molecular biology - 30 Jun 2000
Polge E, Darlix J L, Paoletti J, Fossé P
Abstract excerpt
Retroviral genomes consist of two identical RNA molecules joined non-covalently near their 5'-ends. Recently, we showed that an imperfect autocomplementary sequence, located in the L3 domain, plays an essential role in avian sarcoma-leukosis virus (ASLV) RNA dimerization in vitro. This sequence can adopt a stem-loop structure and is involved in ASLV replication. Here, we found that in the absence of nucleocapsid...
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