Article
Analytical study of rat retrotransposon VL30 RNA dimerization in vitro and packaging in murine leukemia virus.
Journal of molecular biology - 29 Jul 1994
Torrent C, Bordet T, Darlix J L
Abstract excerpt
A sequence of the rat retrotransposon virus-like 30 S RNA (VL30) located next to the 5' end of the Harvey murine sarcoma virus (HaMSV) genome was recently found to form stable dimeric RNA in vitro and to direct the efficient packaging of VL30-derived recombinant RNAs into MuLV virions. To study the structure-function relationships of the rat VL30 dimerization-encapsidation signal (E/DLS), we have performed...
Topics
- 3T3 Cells
- Animals
- Base Sequence
- DNA Transposable Elements
- Gene Products, gag
- Leukemia Virus, Murine
- Lithium Chloride
- Mice
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
