Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Anti-leukaemic and anti-mutagenic effects of di(2-ethylhexyl)phthalate isolated from Aloe vera Linne.

The Journal of pharmacy and pharmacology - 1 May 2000

Lee K H, Kim J H, Lim D S, Kim C H

Abstract excerpt

Extracts of Aloe vera Linne have been found to exhibit cytotoxicity against human tumour cell lines. This study examines the anti-tumour effects of di(2-ethylhexyl)phthalate (DEHP) isolated from Aloe vera Linne, in human and animal cell lines. Its anti-mutagenic effects were examined using Salmonella typhimurium TA98 and TA100 strains. Growth inhibition was specifically exerted by DEHP against three leukaemic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimutagenic Agents
Share to Antineoplastic Agents, Phytogenic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Screening Assays, Antitumor

Share to Phytotherapy

Share to Plant Extracts

Share to Plants, Medicinal

Share to Salmonella typhimurium

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 10864149
DOI: 10.1211/0022357001774246

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Anti-leukaemic and anti-mutagenic effects of di(2-ethylhexyl)phthalate isolated from Aloe vera Linne.PMID 10864149Read ↗

Reduced camptothecin sensitivity of estrogen receptor‐positive human breast cancer cells following exposure to di(2‐ethylhexyl)phthalate (DEHP) is associated with DNA methylation changesSemantic proximity Read ↗

Genotoxicity of 3,6-dinitrobenzo[e]pyrene, a novel mutagen in ambient air and surface soil, in mammalian cells in vitro and in vivo.Semantic proximity Read ↗

Cytotoxic activity of 9,10-dihydro-2,5-dimethoxyphenanthrene-1,7-diol from Eulophia nuda against human cancer cellsSemantic proximity Read ↗

Structural requirements for mutation formation from polycyclic aromatic hydrocarbon dihydrodiol epoxides in their interaction with food chemopreventive compounds.Semantic proximity Read ↗

Evaluation of the in vitro antimutagenic effect of Doash tea aqueous extracts.Semantic proximity Read ↗

Toxicological impact of JWH-018 and its phase I metabolite N-(3-hydroxypentyl) on human cell linesSemantic proximity Read ↗

Mutagenicity, antimutagenicity and cytotoxicity evaluation of South African Podocarpus species.Semantic proximity Read ↗

Evaluation of Genotoxicity by Micronucleus Assay in vitro and by Allium cepa Test in vivoSemantic proximity Read ↗

Modulatory effects of a tannin fraction isolated from Terminalia arjuna on the genotoxicity of mutagens in Salmonella typhimurium.Semantic proximity Read ↗

Study of mutagenicities of phthalic acid and terephthalic acid using in vitro and in vivo genotoxicity tests.Semantic proximity Read ↗

Cell-transforming activity and mutagenicity of 5 phytoestrogens in cultured mammalian cells.Semantic proximity Read ↗

Mutagenicity of benzo[a]pyrene and dibenzopyrenes in the Salmonella typhimurium TM677 and the MCL-5 human cell forward mutation assays.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.