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Article

A tumor suppressor locus in familial and sporadic chordoma maps to 1p36

1 Jan 2000

Abstract excerpt

Previous cytogenetic/FISH data have demonstrated 1p36 deletions in a relapsing familial clivus chordoma developed by a patient who has 2 daughters, respectively affected with childhood astrocytoma and clivus chordoma. Using an approach that combined the LOH (loss of heterozygosity) study of the father chordoma and the daughter astrocytoma and a segregation analysis from parents to sibs using 17 CA-repeats...

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PMID: 10861454
DOI: 10.1002/1097-0215(20000701)87:1<68::aid-ijc10>3.0.co;2-v

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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