Article
Virulence and mutation rates of Salmonella typhimurium strains with increased mutagenic strength in a mouse model.
FEMS microbiology letters - 15 Jun 2000
Campoy S, Pérez de Rozas A M, Barbé J, Badiola I
Abstract excerpt
Two strains of Salmonella typhimurium presenting increased mutation rates, either spontaneous or mediated by DNA damage, have been constructed. One of the strains carries a null mutS mutation, while the other harbors plasmid pRW30, which contains the Escherichia coli umuDC operon. The virulence of these strains has been determined by inoculating BALB/c or Swiss mice. The 50% lethal dose of both strains is...
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