Positive R plasmid mutator effect on chromosomal mutation to nalidixic acid resistance in nalidixic acid-exposed cultures of Escherichia coli.

doi:10.1093/jac/35.5.603

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Article

Positive R plasmid mutator effect on chromosomal mutation to nalidixic acid resistance in nalidixic acid-exposed cultures of Escherichia coli.

The Journal of antimicrobial chemotherapy - 1 May 1995

Ambler J E, Pinney R J

Abstract excerpt

Mutation frequencies to nalidixic acid resistance (15 mg/L in nutrient agar) were determined for derivatives of Escherichia coli AB1157 carrying the mutator plasmids R46, R391 or pYD1, or the non-mutator plasmid RP4. Frequencies of mutation remained constant in cultures of AB1157(R46) growing exp...

Topics

Conjugation, Genetic
DNA Mutational Analysis
Drug Resistance, Microbial
Escherichia coli
Mutation
Nalidixic Acid
R Factors

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