Article
HIV-1 genotypic and phenotypic resistance.
Clinics in laboratory medicine - 1 Sept 2002
Hanna George J
Abstract excerpt
Antiretroviral failure caused by the development of drug resistance in HIV-1 is an increasingly common clinical problem. Two types of resistance assays are available to clinicians. Genotypic assays determine the presence of mutations associated with drug resistance. The interpretation of mutations is often complicated, however, and may require expert opinion. Phenotypic assays provide a direct measure of the drug...
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