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Article

Lack of BCL10 mutations in Hodgkin's disease-derived cell lines.

British journal of haematology - 1 May 2000

Re D, Benenson E, Wolf J, Diehl V, Staratschek-Jox A

Abstract excerpt

The pathogenetic events leading to the malignant transformation of Hodgkin-Reed-Sternberg cells are unknown. As Hodgkin-Reed-Sternberg cells are resistant to CD95-mediated apoptosis and chromosomal aberrations involving the 1p22 region harbouring the proapoptotic BCL10 gene represent a recurrent...

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Topics

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Share to Adaptor Proteins, Signal Transducing
Share to Cell Line, Transformed
Share to Chromosome Aberrations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 1

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Share to Neoplasm Proteins

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 10848834
DOI: 10.1046/j.1365-2141.2000.02052.x

Genes

BCL10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10848834-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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