Article
Expression of yeast INM1 encoding inositol monophosphatase is regulated by inositol, carbon source and growth stage and is decreased by lithium and valproate.
Molecular microbiology - 1 May 2000
Murray M, Greenberg M L
Abstract excerpt
Inositol monophosphatase plays a vital role in the de novo biosynthesis of inositol and in the phosphoinositide second messenger signalling pathway. We cloned the Saccharomyces cerevisiae open reading frame (ORF) YHR046c (termed INM1), which encodes inositol monophosphatase, characterized the protein Inm1p and analysed expression of the INM1 gene. INM1 was expressed in bacteria under the control of the lacZ...
Topics
- Amino Acid Sequence
- Animals
- Carbon
- Cattle
- Escherichia coli
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Fungal
- Genotype
- Humans
- Inositol
- Lithium
- Molecular Sequence Data
- Open Reading Frames
- Phosphoric Monoester Hydrolases