Article
Exogenous inositol and genes responsible for inositol transport are required for mating and sporulation in Shizosaccharomyces pombe.
Current genetics - 1 Apr 1998
Niederberger C, Gräub R, Schweingruber A M, Fankhauser H, Rusu M, Poitelea M, Edenharter L, Schweingruber M E
Abstract excerpt
Fission yeast, Schizosaccharomyces pombe, is a natural inositol auxotroph. We show here that the amount of exogenous inositol added to the medium is critical for the control of its life cycle. Above growth-limiting concentrations inositol stimulates mating and sporulation in minimal medium. The effect of inositol is also observed on yeast-extract-medium plates. We selected a mutant, IM49, which mates and...
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