Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Angiostatin generation by human tumor cell lines: Involvement of plasminogen activators

15 Jun 2000

Abstract excerpt

Angiostatin is a tumor-derived angiogenesis inhibitor consisting of an internal fragment of plasminogen. Little is known about the production of angiostatin by human tumors. In this study, we examined the in vitro angiostatin-generating capacities of a panel of human tumor cell lines (total n = 75) and the proteolytic molecule(s) involved. Angiostatin formation was determined by assessing the level of plasminogen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis and VEGF in Cancer
Share to Cell Adhesion Molecules Research
Share to Protease and Inhibitor Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10842188
DOI: 10.1002/(sici)1097-0215(20000615)86:6<760::aid-ijc2>3.0.co;2-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Angiostatin generation by human tumor cell lines: Involvement of plasminogen activatorsPMID 10842188Read ↗

Matrix metalloproteinase-19 inhibits growth of endothelial cells by generating angiostatin-like fragments from plasminogenSemantic proximity Read ↗

Protease activity of urokinase and tumor progression in a syngeneic mammary cancer model.Semantic proximity Read ↗

Role of plasminogen activator inhibitor-1 in urokinase's paradoxical in vivo tumor suppressing or promoting effects.Semantic proximity Read ↗

The up-regulation of vascular endothelial growth factor in mutated Ha-ras HaCaT cell lines is reduced by a farnesyl transferase inhibitor.Semantic proximity Read ↗

Recombinant PAI-1 inhibits angiogenesis and reduces size of LNCaP prostate cancer xenografts in SCID mice.Semantic proximity Read ↗

The angiogenic switch in hamster buccal pouch keratinocytes is dependent on TGFbeta-1 and is unaffected by ras activation.Semantic proximity Read ↗

A neuroprotective role for angiogenin in models of Parkinson’s diseaseSemantic proximity Read ↗

Angiocrine endothelium: from physiology to cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.