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Article

Mutagen sensitivity and environmental exposures as contributing causes of chromosome 3p losses in head and neck cancers.

Carcinogenesis - 1 Jun 2000

Schantz S P, Huang Q, Shah K, Murty V V, Hsu T C, Yu G, Andersen P E, Huvos A G, Chaganti R S

Abstract excerpt

The interaction between environmental exposures and host susceptibility may lead to specific mutational events within head and neck squamous cell carcinoma (HNSCC). Furthermore, this interplay may determine not only the probability of cancer development but also the biologic characteristics of the tumor once it occurs. To better understand the relationship of mutagen sensitivity and tobacco and/or alcohol...

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PMID: 10837016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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