Article
[HIV-1 (human immunodeficiency virus type 1) mutant strain associated with zidovudine resistance detected from a Japanese patient with primary HIV-1 infection].
Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases - 1 Apr 2000
Usuku S, Noguchi Y, Sakamoto M, Sagara H, Sudo K, Kondo M, Imai M
Abstract excerpt
Sequences of HIV-1 pol gene were determined by direct sequencing from a Japanese patient with primary HIV-1 infection. The patient did not receive antiretroviral therapies. However we observed a HIV-1 mutant strain associated with zidovudine (ZDV) resistance. The patient had both the codon 70 and the codon 215 amino acid substitutions in the RT region. Our data indicated that the patient was infected with a HIV-1...
Topics
- Acquired Immunodeficiency Syndrome
- Anti-HIV Agents
- Drug Resistance, Microbial
- HIV
- Humans
- Japan
- Mutation
- Zidovudine