Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Adeno-associated and Herpes Simplex Viruses as Vectors for Gene Transfer to the Corneal Endothelium

1 May 2000

Abstract excerpt

PURPOSE: We examined the efficacy and cytopathogenicity of adeno-associated (AAV) and herpes simplex viruses (HSV) as vectors for gene transfer to corneal endothelial cells (CECs). METHODS: Recombinant AAV and HSV were examined for their ability to deliver a lacZ histochemical marker gene to whole-thickness rabbit and human corneas ex vivo. Transgene expression was detected with histochemistry and quantified by a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Corneal Surgery and Treatments
Share to Retinal Development and Disorders
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10832701
DOI: 10.1097/00003226-200005000-00022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Adeno-associated and Herpes Simplex Viruses as Vectors for Gene Transfer to the Corneal EndotheliumPMID 10832701Read ↗

Improved transduction of human corneal epithelial progenitor cells with cell-targeting adenoviral vectors.Semantic proximity Read ↗

Efficient and sustained transgene expression in human corneal cells mediated by a lentiviral vectorSemantic proximity Read ↗

Novel adeno-associated viral vectors for retinal gene therapySemantic proximity Read ↗

Ocular Gene Transfer with Self-Complementary AAV VectorsSemantic proximity Read ↗

Immunology of AAV-Mediated Gene Transfer in the EyeSemantic proximity Read ↗

Potential long-term inhibition of ocular neovascularisation by recombinant adeno-associated virus-mediated secretion gene therapySemantic proximity Read ↗

Corneal Transduction by Intra-Stromal Injection of AAV Vectors In Vivo in the Mouse and Ex Vivo in Human ExplantsSemantic proximity Read ↗

Corneal Gene Therapy: Basic Science and Translational PerspectiveSemantic proximity Read ↗

Novel AAV serotypes for improved ocular gene transferSemantic proximity Read ↗

Meganuclease targeting HSV-1 protects against herpetic keratitis: Application to corneal transplantsSemantic proximity Read ↗

Corneal gene therapySemantic proximity Read ↗

Periocular injection of an adenoviral vector encoding pigment epithelium-derived factor inhibits choroidal neovascularizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.