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Article

Improved transduction of human corneal epithelial progenitor cells with cell-targeting adenoviral vectors.

Experimental eye research - 1 Oct 2006

Chen Zhuo, Mok Hoyin, Pflugfelder Stephen C, Li De-Quan, Barry Michael A

Abstract excerpt

The development of vectors and techniques to transfer therapeutic genes to corneal epithelium has broad clinical applications. To determine if adenoviral (Ad5) vectors could be tailored to increase transduction of corneal epithelial progenitor cells expressing epidermal growth factor receptor (EGFR), the feasibility of targeting gene therapy vectors to genetically modify primary cultured human corneal epithelial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16793039
DOI: 10.1016/j.exer.2006.03.023
PMCID: PMC2906397

Genes

EGF
EGFR
ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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