Article
PCR detection of host and HIV-1 sequences from archival brain tissue.
Journal of neurovirology - 1 Apr 2000
Smith K M, Crandall K A, Kneissl M L, Navia B A
Abstract excerpt
Mutations in CCR5 and CCR2b have been recently shown to affect disease progression towards AIDS. A role for these host genotypes in AIDS dementia complex (ADC) has also been postulated but remains unclear. Additionally, brain-derived envelope sequences from HIV-1 have been associated with ADC but their specific contribution to pathogenesis remains uncertain. This study demonstrates the successful use of PCR...
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