Article
Molecular and pathologic insights from latent HIV-1 infection in the human brain
13 Mar 2013
Abstract excerpt
OBJECTIVE: We aimed to investigate whether HIV latency in the CNS might have adverse molecular, pathologic, and clinical consequences. METHODS: This was a case-control comparison of HIV-1 seropositive (HIV+) patients with clinical and neuropathologic examination. Based on the levels of HIV-1 DNA, RNA, and p24 in the brain, cases were classified as controls, latent HIV CNS infection, and HIV encephalitis (HIVE)....