Article
The D allele of the ACE I/D common gene variant is associated with Type 2 diabetes mellitus in Caucasian subjects.
Molecular genetics and metabolism - 1 Jan 2005
Stephens Jeffrey W, Dhamrait Sukhbir S, Cooper Jaqueline A, Acharya Jayshree, Miller George J, Hurel Steven J, Humphries Steve E
Abstract excerpt
The deletion D allele of the angiotensin-I converting enzyme (ACE) I/D gene variant is associated with higher ACE activity in Caucasians and previous studies in non-Caucasian samples have suggested an association between the D allele and type 2 diabetes (Type 2DM). The aim of this study was to compare the genotype distribution between Caucasian subjects with Type 2DM and non-diabetic Caucasian men. Genotype...
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