Gaping lids, gp, a mutation on centromeric chromosome 11 that causes defective eyelid development in mice.

Abstract excerpt

In mammals, during fetal development, the eyelids grow and flatten over the eyes and temporarily fuse closed. Failure of this normal developmental process in mice leads to the defect, open-eyelids-at-birth. Nearly all newborns of the GP/Bc strain, homozygous for the spontaneous recessive mutation, gaping lids (gp), have bilateral open eyelids at birth, with essentially no fusion between the upper and lower...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Animals, Newborn
• Share to Centromere