Article
Pathogenesis of preeclampsia: the genetic component.
Journal of pregnancy - 1 Jan 2012
Valenzuela Francisco J, Pérez-Sepúlveda Alejandra, Torres María J, Correa Paula, Repetto Gabriela M, Illanes Sebastián E
Abstract excerpt
Preeclampsia (PE) is one of the main causes of maternal and fetal morbidity and mortality in the world, causing nearly 40% of births delivered before 35 weeks of gestation. PE begins with inadequate trophoblast invasion early in pregnancy, which produces an increase in oxidative stress contributing to the development of systemic endothelial dysfunction in the later phases of the disease, leading to the...
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