Article
Mutational analysis of the sbo-alb locus of Bacillus subtilis: identification of genes required for subtilosin production and immunity.
Journal of bacteriology - 1 Jun 2000
Zheng G, Hehn R, Zuber P
Abstract excerpt
The Bacillus subtilis 168 derivative JH642 produces a bacteriocin, subtilosin, which possesses activity against Listeria monocytogenes. Inspection of the amino acid sequence of the presubtilosin polypeptide encoded by the gene sboA and sequence data from analysis of mature subtilosin indicate that the precursor subtilosin peptide undergoes several unique and unusual chemical modifications during its maturation...
Topics
- Amino Acid Sequence
- Anti-Bacterial Agents
- Bacillus subtilis
- Bacterial Proteins
- Bacteriocins
- Base Sequence
- Carrier Proteins
- Drug Resistance, Microbial
- Genes, Bacterial
- Molecular Sequence Data
- Mutation
- Peptides
- Peptides, Cyclic
- Phenotype