Article
Isolation of a variant of subtilosin A with hemolytic activity.
Journal of bacteriology - 1 Sept 2009
Huang Tai, Geng Hao, Miyyapuram Venugopal R, Sit Clarissa S, Vederas John C, Nakano Michiko M
Abstract excerpt
Bacillus subtilis produces an anionic bacteriocin called subtilosin A that possesses antibacterial activity against certain gram-positive bacteria. In this study, we uncovered a hemolytic mutant of B. subtilis that produces an altered form of subtilosin A. The mutant bacteriocin, named subtilosin A1, has a replacement of threonine at position 6 with isoleucine. In addition to the hemolytic activity, subtilosin A1...
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