Article
Sequence diversity of Pseudomonas aeruginosa: impact on population structure and genome evolution.
Journal of bacteriology - 1 Jun 2000
Kiewitz C, Tümmler B
Abstract excerpt
Comparative sequencing of Pseudomonas aeruginosa genes oriC, citS, ampC, oprI, fliC, and pilA in 19 environmental and clinical isolates revealed the sequence diversity to be about 1 order of magnitude lower than in comparable housekeeping genes of Salmonella. In contrast to the low nucleotide substitution rate, the frequency of recombination among different P. aeruginosa genotypes was high, leading to the random...
Topics
- Biological Evolution
- Deoxyribonucleases, Type II Site-Specific
- Genes, Bacterial
- Genetic Code
- Genetic Variation
- Genome, Bacterial
- Genotype
- Pseudomonas aeruginosa
- Restriction Mapping
- Sequence Analysis, DNA
- Species Specificity
