Article
Single-Nucleotide Polymorphism-Based Genetic Diversity Analysis of Clinical Pseudomonas aeruginosa Isolates.
Genome biology and evolution - 1 Apr 2020
Muthukumarasamy Uthayakumar, Preusse Matthias, Kordes Adrian, Koska Michal, Schniederjans Monika, Khaledi Ariane, Häussler Susanne
Abstract excerpt
Extensive use of next-generation sequencing has the potential to transform our knowledge on how genomic variation within bacterial species impacts phenotypic versatility. Because different environments have unique selection pressures, they drive divergent evolution. However, there is also parallel or convergent evolution of traits in independent bacterial isolates inhabiting similar environments. The application...
Topics
- Adaptation, Physiological
- Genome, Bacterial
- Humans
- Phenotype
- Phylogeny
- Polymorphism, Single Nucleotide
- Pseudomonas aeruginosa