Article
Genetic, immunohistochemical, and clinical features of medullary carcinoma of the pancreas: A newly described and characterized entity.
The American journal of pathology - 1 May 2000
Wilentz R E, Goggins M, Redston M, Marcus V A, Adsay N V, Sohn T A, Kadkol S S, Yeo C J, Choti M, Zahurak M, Johnson K, Tascilar M, Offerhaus G J, Hruban R H, Kern S E
Abstract excerpt
Medullary carcinomas of the pancreas are a recently described, histologically distinct subset of poorly differentiated adenocarcinomas that may have a unique pathogenesis and clinical course. To further evaluate these neoplasms, we studied genetic, pathological, and clinical features of 13 newly identified medullary carcinomas of the pancreas. Nine (69%) of these had wild-type K-ras genes, and one had...
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