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Pancreatic medullary carcinoma developed on a pancreatic intraductal papillary mucinous neoplasm with loss of MSH2 and MSH6 expression: a case report.

Diagnostic pathology - 13 Dec 2021

Verocq Camille, Racu Marie-Lucie, Bafort Dominique, Butorano Gloria, Perez-Casanova Garcia Luis, Navez Julie, Witterwulghe Marc, Sheahan Kieran, Swan Niall, Closset Jean, Van Laethem Jean-Luc, Maris Calliope, D'Haene Nicky

Abstract excerpt

BACKGROUND: Pancreatic medullary carcinoma (PMC) is a rare pancreatic tumor, usually showing the presence of microsatellite instability, mostly MLH1 silencing, and a wild-type KRAS mutation status. We report here a PMC arising from a Pancreatic Intraductal Papillary Mucinous Neoplasm (IPMN), both having KRAS and TP53 mutations. CASE PRESENTATION: We report the case of a 73-year-old woman presenting with right...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34895278
DOI: 10.1186/s13000-021-01178-0
PMCID: PMC8667442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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