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Article

Molecular evolution and diversity in Bacillus anthracis as detected by amplified fragment length polymorphism markers.

Journal of bacteriology - 1 Feb 1997

Keim P, Kalif A, Schupp J, Hill K, Travis S E, Richmond K, Adair D M, Hugh-Jones M, Kuske C R, Jackson P

Abstract excerpt

Bacillus anthracis causes anthrax and represents one of the most molecularly monomorphic bacteria known. We have used AFLP (amplified fragment length polymorphism) DNA markers to analyze 78 B. anthracis isolates and six related Bacillus species for molecular variation. AFLP markers are extremely sensitive to even small sequence variation, using PCR and high-resolution electrophoresis to examine restriction...

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Identifiers

PMID: 9006038
DOI: 10.1128/jb.179.3.818-824.1997
PMCID: PMC178765

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