Article
Association of apolipoprotein E polymorphism with plasma lipids and Alzheimer's disease in a Southern Brazilian population.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 May 2000
de-Andrade F M, Larrandaburu M, Callegari-Jacques S M, Gastaldo G, Hutz M H
Abstract excerpt
Apolipoprotein E (protein: apo E; gene: APOE) plays an important role in the multifactorial etiology of both Alzheimer's disease (AD) and lipid level concentrations. The polymerase chain reaction (PCR) was used to investigate the APOE gene polymorphism in 446 unrelated Caucasians, among them 23 AD patients, and 100 Afro-Brazilians living in Porto Alegre, Brazil. The frequencies of the APOE*2, APOE*3 and APOE*4...
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