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Article

The ETS family member Tel antagonizes the Fli-1 phenotype in hematopoietic cells.

Blood cells, molecules & diseases - 1 Feb 2000

Kwiatkowski B A, Zielinska-Kwiatkowska A G, Bauer T R, Hickstein D D

Abstract excerpt

The ETS family member Tel is rearranged in human leukemia of both myeloid and lymphoid origin while the ETS member Fli-1 is insertionally activated in Friend erythroleukemia in mice and is translocated to the EWS locus in Ewing's sarcoma. In previous studies we demonstrated that Tel binds to Fli-1 and blocks transactivation of megakaryocytic promoters by Fli-1. In this study we demonstrate that expression of...

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Share to ETS Translocation Variant 6 Protein
Share to Hematopoietic Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to K562 Cells

Share to Megakaryocytes

Share to Platelet Glycoprotein GPIb-IX Complex

Share to Platelet Glycoprotein GPIIb-IIIa Complex

Share to Proto-Oncogene Protein c-fli-1

Share to Proto-Oncogene Proteins c-ets

Source

Identifiers

PMID: 10772879
DOI: 10.1006/bcmd.2000.0282

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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