Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of an Isogenic Mutant of <i>Streptococcus pyogenes</i> Manfredo Lacking the Ability To Make Streptococcal Acid Glycoprotein

1 May 2000

Abstract excerpt

An isogenic mutant of Streptococcus pyogenes Manfredo that lacks the ability to make streptococcal acid glycoprotein (SAGP) has been constructed by inserting a deletion in the sagp gene using the method of allelic exchange. An assay of cell extracts (CE) prepared from the wild-type and mutant Manfredo strains for the enzyme arginine deiminase (AD) showed that significant activity was present in wild-type CE but...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Infective Endocarditis Diagnosis and Management
Share to Streptococcal Infections and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10768929
DOI: 10.1128/iai.68.5.2441-2448.2000

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Characterization of an Isogenic Mutant of <i>Streptococcus pyogenes</i> Manfredo Lacking the Ability To Make Streptococcal Acid GlycoproteinPMID 10768929Read ↗

Expression of different group A streptococcal M proteins in an isogenic background demonstrates diversity in adherence to and invasion of eukaryotic cells.Semantic proximity Read ↗

Combined Contributions of Streptolysin O and Streptolysin S to Virulence of Serotype M5Streptococcus pyogenesStrain ManfredoSemantic proximity Read ↗

Role of M protein in adherence of group A streptococciSemantic proximity Read ↗

Genetic inactivation of the extracellular cysteine protease enhances in vitro internalization of group A streptococci by human epithelial and endothelial cells.Semantic proximity Read ↗

Proteins M6 and F1 are required for efficient invasion of group A streptococci into cultured epithelial cells.Semantic proximity Read ↗

Disease-attenuated pneumococcal biosynthesis gene mutants invade the mucosal epithelium and induce innate immunitySemantic proximity Read ↗

Increased Pilus Production Conferred by a Naturally Occurring Mutation Alters Host-Pathogen Interaction in Favor of Carriage in Streptococcus pyogenesSemantic proximity Read ↗

NAD+‐glycohydrolase acts as an intracellular toxin to enhance the extracellular survival of group A streptococciSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.