Back to the roots of a new exon--the molecular archaeology of a SP100 splice variant.

doi:10.1006/geno.1999.6008

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Back to the roots of a new exon--the molecular archaeology of a SP100 splice variant.

Genomics - 1 Jan 2000

Rogalla P, Kazmierczak B, Flohr A M, Hauke S, Bullerdiek J

Abstract excerpt

Retropseudogenes are intronless DNA sequences sharing a high degree of homology with the cDNA of their corresponding active genes. They are thought to have originated by reverse transcription of messenger RNA and reintegration of the cDNA into the genome. Usually considered a type of evolutionary waste, they melt into the background of their surrounding DNA by the loss of similarity to the active gene or...

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Back to the roots of a new exon--the molecular archaeology of a SP100 splice variant.

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