Article
Molecular archeology of an SP100 splice variant revisited: dating the retrotranscription and Alu insertion events.
Genome biology - 1 Jan 2001
Devor E J
Abstract excerpt
BACKGROUND: SP100 is a nuclear protein that displays a number of alternative splice variants. In Old World monkeys, apes and humans one of these variants is extended by a retroprocessed pseudogene, HMG1L3, whose antecedent gene is a member of the family of high-mobility-group proteins, HMG1. This is one of only a few documented cases of a retropseudogene being incorporated into another gene as a functional exon....
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