Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Localization to Chromosome 1p32 of the Third Locus for Familial Hypercholesterolemia in a Utah Kindred

1 Apr 2000

Abstract excerpt

Clinical familial hypercholesterolemia has been shown to result from mutations in 2 genes, the low density lipoprotein (LDL) receptor on chromosome 19 and apolipoprotein B on chromosome 2. However, we have recently described a Utah pedigree in which linkage to both genes was clearly excluded. A multipoint linkage analysis of 583 markers genotyped on 31 (18 affected) members of this pedigree was undertaken to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes, Cardiovascular Risks, and Lipoproteins
Share to Genetic Associations and Epidemiology
Share to Lipoproteins and Cardiovascular Health

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10764678
DOI: 10.1161/01.atv.20.4.1089

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Localization to Chromosome 1p32 of the Third Locus for Familial Hypercholesterolemia in a Utah KindredPMID 10764678Read ↗

Replication of linkage of familial hypobetalipoproteinemia to chromosome 3p in six kindreds.Semantic proximity Read ↗

Linkage of a gene for familial hypobetalipoproteinemia to chromosome 3p21.1-22.Semantic proximity Read ↗

Evidence of linkage of familial hypoalphalipoproteinemia to a novel locus on chromosome 11q23.Semantic proximity Read ↗

A mutation in PCSK9 causing autosomal-dominant hypercholesterolemia in a Utah pedigree.Semantic proximity Read ↗

Evidence for a third genetic locus causing familial hypercholesterolemia. A non-LDLR, non-APOB kindred.Semantic proximity Read ↗

Fine mapping of low-density lipoprotein receptor gene by genetic linkage on chromosome 19p13.1-p13.3 and study of the founder effect of four French Canadian low-density lipoprotein receptor gene mutations.Semantic proximity Read ↗

Enhanced linkage of a locus on chromosome 2 to premature coronary artery disease in the absence of hypercholesterolemia.Semantic proximity Read ↗

A novel LDLR mutation, H190Y, in a Utah kindred with familial hypercholesterolemia.Semantic proximity Read ↗

Identification of a common variant in the lipoprotein lipase gene in a large Utah kindred ascertained for coronary heart disease: the -93G/D9N variant predisposes to low HDL-C/high triglycerides.Semantic proximity Read ↗

Evidence for a gene influencing high-density lipoprotein cholesterol on chromosome 4q31.21.Semantic proximity Read ↗

Genetic basis of familial dyslipidemia and hypertension: 15-year results from Utah.Semantic proximity Read ↗

Preliminary localization of a gene for autosomal dominant hypoparathyroidism to chromosome 3q13.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.