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Article

Singular subsets of locus coeruleus neurons may recover tyrosine hydroxylase phenotype transiently expressed during development.

Brain research. Molecular brain research - 29 Mar 2000

Bezin L, Marcel D, Desgeorges S, Pujol J F, Weissmann D

Abstract excerpt

The number of tyrosine hydroxylase (TH)-expressing neurons appears to be precisely determined in basal conditions within the noradrenergic pontine nucleus locus coeruleus (LC). However, additional neurons exhibiting TH phenotype have been observed in the adult rat LC following a single administration of RU 24722, a potent inducer of TH expression specific to the LC. The neurons acquiring TH phenotype following...

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PMID: 10762702
DOI: 10.1016/s0169-328x(00)00007-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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