Article
Plasticity of tyrosine hydroxylase gene expression within BALB/C and C57Black/6 mouse locus coeruleus.
Neuroscience letters - 13 Feb 1998
Marcel D, Raison S, Bezin L, Pujol J F, Weissmann D
Abstract excerpt
The plasticity of tyrosine hydroxylase (TH) phenotype in the locus coeruleus (LC) of two pure inbred strains of mice, Balb/C (C) and C57Black/6 (B6), was investigated at the molecular level by radioactive in situ hybridization. The results demonstrated that in basal conditions, C mouse LC contains less TH-mRNA-expressing cells than B6. After RU 24722-treatment, which induces long lasting TH gene expression in the...
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