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Article

Balancing selection at closely linked, overdominant loci in a finite population.

Genetics - 1 Mar 2000

Slatkin M

Abstract excerpt

High levels of allelic diversity and strong linkage disequilibrium are found in the major histocompatibility (MHC) system in humans and other vertebrates. This article proposes several descriptive statistics that quantify the extent and pattern of strong linkage disequilibrium between pairs of highly polymorphic loci. It also develops an approximate analytic theory incorporating the effects of balancing...

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Share to Genes, Dominant
Share to HLA-DQ alpha-Chains

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Source

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Identifiers

PMID: 10757776
DOI: 10.1093/genetics/154.3.1367
PMCID: PMC1460987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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