Article
Phlebotomy increases cadmium uptake in hemochromatosis.
Environmental health perspectives - 1 Apr 2000
Akesson A, Stål P, Vahter M
Abstract excerpt
The intestinal absorption of the nephrotoxic environmental pollutant cadmium increases markedly when iron stores are depleted. This may be mediated by an up regulation of the recently identified mucosal transporter DMT1 (Nramp2 or DCT1) for divalent cations. We tested whether the highly increased iron absorption in hereditary hemochromatosis (HH) was accompanied by an enhanced absorption of cadmium and lead....
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